What are the main benefits of Etidronic Acid?
Etidronic acid (Etidronic Acid) is a medicine commonly used by physicians. Its main functions are three, one is to resist bone resorption, the other is to regulate calcium metabolism, and the third is to prevent ectopic ossification.
The ability to resist bone resorption is really the key. In bone, there is always a dynamic balance between bone resorption and bone formation in the body. If bone resorption is excessive, various bone diseases will occur, such as osteoporosis. Etidronic acid can enter osteoclasts, prevent their dissolution and absorption of bone matrix, and slow down the rate of bone resorption. Osteoclasts are responsible for bone resorption, but etdronic acid inhibits its activity, maintains the stability of bone mass, and makes the strength and structure of bone normal. It is a good medicine for the prevention and treatment of osteoporosis.
Regulating calcium metabolism is also its function. Calcium has a great function in the body, which is related to nerve conduction, muscle contraction and many other physiological factors. Etidronic acid can be combined with calcium to regulate the absorption, excretion and deposition of calcium in the intestines, kidneys and bones. In the intestines, it can reduce the absorption of calcium; in the kidneys, it can increase the excretion of calcium; in the bones, it can promote the deposition of calcium. After this adjustment, the blood calcium concentration is constant in the normal domain, maintaining the stability of the body's physiology.
Furthermore, the power of preventing ectopic ossification is also apparent. Ectopic ossification is a disease of abnormal formation of bone tissue in parts other than normal bone tissue. Etidronic acid can inhibit the deposition of calcium salts in soft tissue, inhibit the activity of osteoblasts, and prevent the formation of heterotopic bone. In the case of trauma, surgery and other situations that are prone to heterotopic ossification, etidronic acid can reduce the possibility of its occurrence, help patients recover, and avoid joint mobility restriction caused by heterotopic ossification.
What are the side effects of Etidronic Acid?
Etidronic acid (Etidronic Acid), although it has the power to treat bone diseases, it also has various side effects, which cannot be ignored.
First, it often disturbs the gastrointestinal tract. Those who use this drug often experience nausea and vomiting, abdominal pain, fullness, and loss of appetite. Because the drug stimulates the gastrointestinal mucosa, causing it to transport and lose its functions, it has all kinds of discomfort.
Second, it also has potential harm to the kidneys. Long-term or excessive use may affect the excretion function of the kidneys. The kidneys main water metabolism, and the drug is excreted through the kidneys. If the kidney is overburdened or causes abnormal renal function indicators, it may even cause substantial damage to the kidneys.
Third, it affects the balance of calcium metabolism. Although etyldronic acid can act on bone metabolism, it may also interfere with the normal absorption and deposition of calcium. Calcium is an important component of bone. If calcium metabolism is unbalanced, the stiffness of bone may be affected, or the risk of fracture may increase, especially in the elderly and osteoporosis, more attention should be paid.
Fourth, some patients may experience skin allergies after taking medication. Such as skin itching and rash, this is an allergic reaction of the body to the drug. Although it may not be serious, it also affects the quality of life of patients.
When using drugs, doctors should also consider the advantages and disadvantages, and use drugs rationally according to the specific conditions of the patient to reduce the harm of side effects and achieve the best curative effect.
What is the correct use of Etidronic Acid?
Etidronic acid (Etidronic Acid), the method of use, must follow the doctor's advice. Its medicine is often used to treat bone diseases, such as osteoporosis, osteitis deformatis and the like.
If osteoporosis is treated with medicine, the method of use is as follows: Oral, the daily dose is often divided into two times, taken on an empty stomach, that is, at least half an hour before meals. In this way, the absorption of the medicine can be better. Because food can reduce its absorption, it must be fasted. The dose varies according to the condition. Generally, when an adult is initially treated, the daily dose is about 5 milligrams per kilogram of body weight, divided into two doses, used for two consecutive weeks, and then stopped for eleven weeks as a course of treatment.
As for the treatment of osteitis deformatis, it is also taken orally. The daily dose for adults is about 5 milligrams per kilogram of body weight. Take it once, and the course of treatment depends on the condition, or it may take several months.
When taking this medicine, you should also pay attention. If you take this medicine, you should drink more water to reduce the irritation of the medicine to the esophagus. If you have difficulty swallowing, chest pain, etc., you should inform a doctor immediately. And this medicine may interact with other medicines. If you take it with calcium, the two will affect the absorption of each other. Therefore, the interval between taking this medicine and taking calcium must be at least two hours. In addition, pregnant women, breastfeeding women and people with renal insufficiency should be especially cautious when using this medicine, and you must follow the method prescribed by the doctor after careful inspection. Do not use it without authorization.
Which groups of people is Etidronic Acid suitable for?
Etidronic acid (Etidronic Acid) is a medicine commonly used by physicians. It is suitable for a wide range of people, the first being those who suffer from osteoporosis. This disease is more common in the elderly. As they grow older, calcium is lost in the bones, and the bones are fragile and easy to break. Etidronic acid can block calcium loss and strengthen the bone, so that the elderly will not suffer from fractures.
Furthermore, it is also suitable for people with deformable osteitis. This disease causes changes in the shape and structure of the bone, and patients often feel bone pain. Etidronic acid can regulate the metabolism of bone, relieve its pain, and restore the normal state of bone.
Also, for patients with heterotopic ossification, Etidronic acid is also effective. In patients with heterotopic ossification, bone grows in abnormal places or hinders joint movement. This medicine can inhibit the formation of abnormal bone and maintain joint agility.
When taking medicine, the doctor must carefully review the patient's condition and weigh the pros and cons. Young people, pregnant women and nursing mothers should be especially cautious when taking medicine, because the effect of etidronic acid on it is not fully understood. Therefore, it is necessary to follow the doctor's advice and not use it without authorization, so as to obtain the appropriate medication and ensure the well-being of the patient.
Does Etidronic Acid Interact with Other Drugs?
Etidronic acid (Etidronic Acid) is often used as a bone metabolism regulator in the field of medicine. As for whether it interacts with other drugs, it needs to be reviewed in detail.
To observe all kinds of drugs, their properties are different. When they meet, they may produce synergistic effects and increase their work; or they may cause antagonistic changes, damage their medicinal power, or even breed toxic side effects. Etidronic acid is no exception.
If taken with calcium, the two can interact in the gastrointestinal tract, causing calcium absorption to be hindered, and the effect of etidronic acid is also reduced. Geyin Etidronic acid has chelating properties, easy to complex with calcium, forming insoluble substances, difficult to absorb.
Furthermore, when used in combination with antacids, there are also concerns. Antacids contain mostly aluminum, magnesium and other ingredients, and ettidronic acid encounters them, or changes the acid-base environment in the gastrointestinal tract, affecting the dissolution and absorption of drugs, and may also occur complexation reactions, resulting in a decrease in the activity of both.
However, if the compatibility is appropriate, it may also have a good effect. If used in combination with certain vitamin drugs, if the vitamin can promote the absorption of ettidronic acid, or help it play a pharmacological role, it can complement each other.
Therefore, when a doctor uses medication, he must study the pharmacology in detail, be familiar with the characteristics of each drug, weigh the pros and cons, and prescribe it cautiously, so that the drug can be used to its fullest extent and avoid harmful effects, so as to ensure the well-being of the patient.